Table 6 Illustrative set of biclusters with different properties and heightened biological relevance ( p -values after Bonferroni correction)
From: BicPAM: Pattern-based biclustering for biomedical data analysis
Dataset | ID | Pattern | Items | Closing options | ||
|---|---|---|---|---|---|---|
| Â | B1 | FAABFFF | A-F | Merging with tight overlapping | ||
dlblc | B2 | AAABCA | A-C | Extensions allowed (with tight merging) | ||
| Â | B3 | AAA/../EEE | A-E | Reducing with high homogeneity | ||
| Â | B4 | EEECEE | A-E | Merging allowed | ||
hughes | B5 | CCDCBCBCC | A-E | Merging with relaxed overlapping | ||
| Â | B6 | AAAAA/../G..G | A-G | Merging with tight overlapping | ||
gasch | B7 | AAAGGGA | A-G | Merging with tight overlapping | ||
| Â | B8 | AAABACCCAA | A-E | Merging allowed | ||
ID | Type | ♯ Genes | ♯ Conds | ♯ p −values <0.01 | ♯ p −values [0.01,0.05] | Best p-value |
B1 | constant | 83 | 7 | 41 | 21 | 1.97E-10 |
B2 | constant | 153 | 8 | 9 | 1 | 2.27E-12 |
B3 | multiplicative | 119 | 5 | 5 | 18 | 4.12E-8 |
B4 | constant | 581 | 6 | 12 | 7 | 1.31E-25 |
B5 | constant | 654 | 10 | 16 | 4 | 1.31E-17 |
B6 | additive | 476 | 6 | 12 | 10 | 1.92E-6 |
B7 | multiplicative | 483 | 7 | 57 | 10 | 1.24E-81 |
B8 | additive | 521 | 10 | 17 | 5 | 4.57E-12 |